Cytokeratin 17 RMab - Mouse EP98BSB 6184-BSB 6190
Cytokeratin 17 is a Type I cytokeratin with a MW of 46 kD found sometimes in association with Cytokeratin 7. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to Jackson-Lawler type Pachyonychia Congenita and Steatocystoma Multiplex. Cytokeratin 17 antibody has been used to distinguish immature Cervical Squamous Metaplasia from high grade Cervical Intraepithelial Neoplasia (CIN III). Anti-CK 17 also labels myoepithelial cells in the benign breast tissue. CK 17 labeling of Breast Carcinoma cells (so-called basal phenotype) has been associated with a poor prognosis.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.