HLA-DRB1 beta chain RMab EP191
Bio SB

HLA-DRB1 beta chain RMab EP191

BSB 2433-BSB 2439

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HLA class II histocompatibility antigen, DRB1-9 beta chain belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. HLA-DRB1 is expressed mainly on antigen-presenting cells, such as B lymphocytes, monyctes and dendritic cells, but can also be detected on activated T lymphocytes and activated granulocytes. In abnormal tissues, HLA-DRB1 has been found in different types of Acute Lymphoblastic Leukemias and Acute Myeloid Leukemias. Additionally, HDLADR was also found in some nonhematopoietic tumors, including carcinomas of the colon and breast.

Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.

For Research Use Only.