ERG Break Apart FISH Probe Kit - 10 tests

The ERG Break Apart FISH Probe Kit is designed to detect rearrangements in the human ERG gene located on chromosome band 21q22.2.* In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other ERG aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the ERG gene – also known as p55 or erg-3 – have been observed in Ewing’s sarcoma, acute myeloid leukemia (AML), prostate cancer and other tumor types.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.