FGFR3 Break Apart FISH Probe Kit - 10 tests

The FGFR3 Break Apart FISH Probe Kit is designed to detect rearrangements in the human FGFR3 gene located on chromosome band 4p16.3.* In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other FGFR3 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the FGFR3 gene – also known as ACH, CEK2, JTK4, CD333 or HSFGFR3EX – have been observed in multiple myeloma, cervical and bladder cancer and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

For Research use Only.