FIP1L1-CHIC2-PDGFRA Tri-color FISH Probe Kit - 10 tests

The FIP1L1-CHIC2-PDGFRA Tri-color FISH Probe Kit is designed to detect rearrangements involving the human FIP1L1, CHIC2 andPDGFRA genes located on chromosome band 4q12.* Rearrangements between the FIP1L1 and PDGFRA genes with an interstitial deletion at the CHIC2 gene region have been observed in diverse eosinophilia-associated hematologic disorders like hyperseosinophilic syndrome (HES), systemic mastocytosis (SM) and chronic eosinophilic leukemia (CEL).

The probe set is labeled with CytoOrange, CytoGreen and CytoAqua. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with an appropriate filter; CytoAqua has an excitation peak at 422 nm and emission peak at 471 nm, giving it an aqua fluorescent signal with an appropriate filter.

For Research Use Only.