CytoTest LSP C19MC FISH ProbeCT-LSP026
The C19MC FISH Probe is designed to detect the human C19MC microRNA cluster locus located on chromosome band 19q13.42.
The C19MC FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.
The C19MC FISH probe hybridizes to chromosome 19 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 19q13.42 region on the chromosome 19. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 19q13.42. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 19.
For Research Use Only.