CytoTest LSP FGFR1 5' FISH ProbeCT-LSP107
The FGFR1 5’ FISH Probe is designed to detect the human FGFR1 gene 5’-region located on chromosome band 8p11.23. FGFR1 is also known as CEK, FLG, HH2, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, FLT-2, HBGFR, N-SAM, FGFR-1, HRTFDS or bFGF-R-1.
The FGFR1 5' FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with the appropriate filters.
The FGFR1 5' FISH probe hybridizes to chromosome 8 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 8p11.23 region on the chromosome 8. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 8p11.23. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 8.
For Research Use Only.