CytoTest LSP FUS 3' FISH ProbeCT-LSP096
The FUS 3’ FISH Probe is designed to detect the human FUS gene 3’-region located on chromosome band 16p11.2. FUS is also known as TLS, ALS6, ETM4, FUS1, POMP75 or HNRNPP2A.
The FUS 3' FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with the appropriate filters.
The FUS 3' FISH probe hybridizes to chromosome 16 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 16p11.2 region on the chromosome 16. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 16p11.2. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 16.
For Research Use Only.