BlueDot ANCA + GBM IgG Kit (IVD)
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BlueDOT ANCA + GBM IgG is an Immunodot kit intended for the detection in human sera of IgG autoantibodies against the Myeloperoxydase (MPO), Proteinase 3 (PR3) and Glomerular Basement Membrane/Collagen IV-?3 antigens. Each kit contains 24 tests.
BlueDot kits are composed of 24 nitrocellulose strips on which the antigens have been coated in a dot-shaped format. One strip allows the testing of one patient for many different autoantibodies in the same run. The test is based on a classical Enzyme ImmunoAssays (EIA).
In addition to the antigens, each strip possesses two built-in reactive controls :
- The first one, the Reaction Control (RC), controls the validity of the test : its coloration proves that the clinician has added the patient serum and that the test has functioned correctly.
- The second one, the Cut-Off Control (CO), allows the interpretation of the test : any color intensity equal to or below that of the cut-off is considered negative, any color intensity superior to that of the cut-off is considered positive.
The results can be interpretated by sight or a semi-quantification can be obtained thanks to the Dr DOT software.