TRAB HUMAN RIA, 100 TESTS

The DIAsource TRAb human kit is used for the quantitative determination of Thyro¬tropin (TSH) receptor autoantibodies in human serum. The majority of TSH receptor autoantibodies (TRAb) mimic the action of TSH on thyroid cells and thus increase blood levels of T4 and T3. Because they are not controlled by the negative feedback system, the stimulation of the thyroid gland often leads to the clinical thyrotoxic state of Graves’ disease. Consequently, the measurement of TRAb is valuable for the differential diagnosis of hyperthyroidism as well as for the follow-up of Graves disease, both during and after its treatment by antithyroid drugs or 131-radioiodine or surgery. Pregnant women developing Graves disease can transfer their autoantibodies to the fetus via the placental unit. The higher the TRAb concentrations of the mother, the greater the risk for the embryo to develop Graves disease in uterus and thus to suffer from congenital hyperthyroidism.

Catalog #: KIPM2040
Format: RIA
Label: I125
Size: 100 tests
Sample Type: Serum
Sample Volume: 100 µL
Controls: 1 level
Range: 0 - 50 IU/ml
Sensitivity: 0,23 IU/ml
Incubation: 120min./60 min.
Shelf Life (weeks): 7.5