Alpha-Fetoprotein - Rabbit polyclonalBSB 5050-BSB 5056
Alpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Positive staining with this antibody is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.