Calcitonin - Rabbit polyclonalBSB 5113-BSB 5119
Calcitonin is a 32-amino acid polypeptide hormone that is produced in humans primarily by C-cells located in the thyroid, and in many other animals in the ultimobranchial gland. It acts to reduce blood calcium (Ca2+), opposing the eff ects of parathyroid hormone (PTH). It has been found in fi sh, reptiles, birds, and mammals. Its importance in humans has not been as well established as in other animals. Immunohistochemical staining with Calcitonin antibody has proven to be an eff ective way of demonstrating the existence of Calcitonin-producing cells in the thyroid. C-cell Hyperplasia and Medullary Thyroid Carcino-mas stain positive for Calcitonin. Studies of Calcitonin have resulted in the identifi cation of a wide spectrum of C-cell proliferative abnormalities.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.