FOXP3 - Rabbit polyclonal

FOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors. Alterations in numbers of regulatory T-cells — in particular those that express FOXP3 — are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.

Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.

For Research Use Only.