MUM1 RMab EP190BSB 6953-BSB 6959
MUM1 (multiple myeloma oncogene-1) also known as interferon regulatory factor 4 (IRF4) is a 50 kDa protein and is a member of the interferon regulatory factor family of transcription factors. It is induced by antigen receptor mediated stimuli and plays an important role in cell proliferation, differentation and survival. MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B-cells commited to plasmacytic or memory cell differentation in the “light zone”. MUM1 is useful for subclassification of lymphoid malignancies and is an excellent marker for Hodgkin’s and Reed-Sternberg cells of classic Hodgin’s disease.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.