MyoD1 RMab EP212BSB 6974-BSB 6980
MyoD1 belongs to a family of proteins known as myogenic regulatory factors (MRFs) and has a key role in regulating muscle differentation. These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MyoD1 is expressed in activated satellite cells, but not in quiescent satellite cells. In development, MyoD1 commits mesoderm cells to a skeletal lineage, and then regulates that process. It may also play a role in muscle repair. In abnormal tissues, MyoD1 labels tumor cells in Rhabdomyosarcoma and is one of the earliest markers of myogenic commitment.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.