Neurofilaments are the Type IV family of intermediate filaments that are found in high concentrations along the axons of vertebrate neurons. Neurofilament antibody identifies an antigen localized in a number of neural, neuroendocrine and endocrine tumors. Neuromas, Ganglioneuromas, Gangliogliomas, Ganglioneuroblastomas and Neuroblastomas stain positively for neurofilament. Neurofilaments are also present in Paragangliomas and Adrenal and Extra-Adrenal Pheochromocytomas. Carcinoids, Neuroendocrine Carcinomas of the Skin, and Oat Cell Carcinomas of the Lung also express neurofilament.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.