SOX-11 - mouse CL0142

Transcription factor SOX-11 is a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis and adult neurogenesis. SOX-11 is normally expressed in the developing human central nervous system, Medulloblastoma, and Glioma. Anti-SOX-11 nuclear protein expression is highly associated with both Cyclin D1-positive and negative Mantle Cell Lymphomas, with a stronger and more homogeneous Immunohistochemistry staining than Cyclin D1. 

Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.

For Research Use Only.