Bio SB TCR Beta F1 - mouse 8A3BSB 2258-2264
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. TCR Beta is a member of the immunoglobin super family and a component of the CD3/TCR complex (along with TCR Alpha).
TCR Beta is expressed by thymocytes and a majority of peripheral (α-β TCR-bearing) T-cells. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors.
Available options include prediluted (3ml, 7 ml, 15ml), concentrate (0.1 ml, 0.5ml, 1ml) and 5+ control slides.
For Research Use Only.