BCL6 Break Apart FISH Probe Kit - 10 tests

BCL6 Break Apart FISH Probe Kit - 10 tests


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The BCL6 Break Apart FISH Probe Kit is designed to detect rearrangements in the human BCL6 gene located on chromosome band 3q27.3. In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other BCL6 aberrations such as deletions or amplifications. Rearrangements of the BCL6 gene – also known as BCL5, LAZ3, BCL6A, ZNF51 or ZBTB27 – have been observed in B-cell lymphomas and leukemias. BCL6 is also dysregulated in multiple myeloma cases and several solid tumor types. More than 30 different translocation partner genes have been described.

For Research Use Only.