CUX1/VIPR2/CCP7 FISH Probe Kit - 10 tests

The CUX1/VIPR2/CCP7 FISH Probe Kit is designed to detect the human CUX1 gene located on chromosome band 7q22.1, and theVIPR2 gene on chromosome band 7q36.3, along with the number of chromosome 7 copies per cell. Expression of the CUX1 gene – also known as CDP, CUX, p75, CASP, CDP1, COY1, Clox, p100, p110, p200, CUTL1, GOLIM6, CDP/Cut, Cux/CDP or Nbla10317 – has been observed elevated in pancreatic, breast and other cancers. Duplications and other anomalies in the region of the VIPR2gene – also called VPAC2, VPAC2R, VIP-R-2, VPCAP2R, PACAP-R3, DUP7q36.3, PACAP-R-3 or C16DUPq36.3 – are associated with schizophrenia, prenatal malformations and some intestinal malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.