ETV4 Break Apart FISH Probe Kit - 10 tests

The ETV4 Break Apart FISH Probe Kit is designed to detect rearrangements in the human ETV4 gene located on chromosome band 17q21.31.* In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other ETV4 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the ETV4 gene – also known as E1AF, PEA3, E1A-F or PEAS3 – have been observed in melanoma, breast, lung, prostate and other cancers.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.