CytoTest LSP ABL2 FISH ProbeCT-LSP033
The ABL2 FISH Probe is designed to detect the human ABL2 gene located on chromosome band 1q25.2. ABL2 is also known as ARG or ABLL.
The ABL2 FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with the appropriate filters.
The ABL2 FISH probe hybridizes to chromosome 1 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 1q25.2 region on the chromosome 1. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 1q25.2. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 1.
For Research Use Only.