CytoTest LSP CDKN2C FISH ProbeCT-LSP068
The CDKN2C FISH Probe is designed to detect the human CDKN2C gene located on chromosome band 1p32.3. CDKN2C is also known as p18, INK4C orp18-INK4C.
The CDKN2C FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with the appropriate filters.
The CDKN2C FISH probe hybridizes to chromosome 1 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 1p32.3 region on the chromosome 1. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 1p32.3. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 1.
For Research Use Only.