LSP CISD2 FISH Probe

The CISD2 FISH Probe is designed to detect the human CISD2 gene located on chromosome band 4q24. CISD2 is also known as ERIS, WFS2, ZCD2, NAF-1 or Miner1.

The CISD2 FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.

The CISD2 FISH probe hybridizes to chromosome 4 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 4q24 region on the chromosome 4.  In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 4q24.  Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 4.

For Research Use Only.