CytoTest LSP CKS1B FISH ProbeCT-LSP067
The CKS1B FISH Probe is designed to detect the human CKS1B gene located on chromosome band 1q21.3. CKS1B is also known as CKS1, ckshs1,PNAS-16 or PNAS-18.
The CKS1B FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.
The CKS1B FISH probe hybridizes to chromosome 1 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 1q21.3 region on the chromosome 1. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 1q21.3. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 1.
For Research Use Only.