CytoTest LSP FGFR3 FISH ProbeCT-LSP192
The FGFR3 FISH Probe is designed to detect the human FGFR3 gene located on chromosome band 4p16.3.
The FGFR3 FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.
The FGFR3 FISH probe hybridizes to chromosome 4 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 4p16.3 region on the chromosome 4. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 4p16.3. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 4.
For Research Use Only.