CytoTest LSP FOXO1 3' FISH ProbeCT-LSP078
The FOXO1 3' FISH Probe is designed to detect the human FOXO1 gene 3'-region located on chromosome band 13q14.11. FOXO1 is also known as FKH1, FKHR or FOXO1A.
The FOXO1 3' FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with the appropriate filters.
The FOXO1 3' FISH probe hybridizes to chromosome 13 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 13q14.11 region on the chromosome 13. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 13q14.11. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 13.
For Research Use Only.