LSP MAF FISH Probe
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The MAF FISH Probe is designed to detect the human MAF gene located on chromosome band 16q23.2. MAF is also known as C-Maf, MGC71685 or c-MAF.
The MAF FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.
The MAF FISH probe hybridizes to chromosome 16 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 16q23.2 region on the chromosome 16. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 16q23.2. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 16.
For Research Use Only.