LSP MAFB FISH Probe

The MAFB FISH Probe is designed to detect the human MAFB gene located on chromosome band 20q12. MAFB is also known as KRML or MCTO.

The MAFB FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.

The MAFB FISH probe hybridizes to chromosome 20 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 20q12 region on the chromosome 20. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 20q12. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 20.

For Research Use Only.