CytoTest LSP MCF2L FISH ProbeCT-LSP020
The MCF2L FISH Probe is designed to detect the human MCF2L gene located on chromosome band 13q34.
The MCF2L FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.
The MCF2L FISH probe hybridizes to chromosome 13 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 13q34 region on the chromosome 13. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 13q34. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 13.
For Research Use Only.