PBX1 Break Apart FISH Probe Kit - 10 testsCT-PAC205
The PBX1 Break Apart FISH Probe Kit is designed to detect rearrangements in the human PBX1 gene located on chromosome band 1q23.3.* In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other PBX1 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the PBX1 gene – also known as PRL – have been observed in B-cell acute lymphoblastic leukemias (B-ALL) and other tumor types.
The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.
For Research Use Only.