PTPRT/CCP20 FISH Probe Kit - 10 tests

The PTPRT/CCP20 FISH Probe Kit is designed to detect the human PTPRT gene located on chromosome band 20q12, along with the number of chromosome 20 copies per cell. Normal function of the PTPRT gene product - also called RPTPrho, PTPrho or PTPρ – is frequently lost in human colon cancers. The gene likely serves as a tumor suppressor gene in colorectal, lung, skin and stomach cancers. The locus is also deleted in some acute leukemias and other myeloproliferative disorders.

he probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.