S100A10/PNOC FISH Probe Kit - 10 tests

The S100A10/PNOC FISH Probe Kit is designed to detect the human S100A10 gene, located on chromosome band 1q21.3, and thePNOC gene on chromosome band 8p21.1. The S100A10 gene – also called 42C, P11, p10, GP11, ANX2L, CAL1L, CLP11, Ca[1] orANX2LG – has been shown to be over-expressed in thyroid, gastric and renal cancers and some lymphomas. It may also play a role in inherited depressive disorders. Mutations of the PNOC gene – also called OFQ, N/OFQ, PPNOC or ppN/OFQ – have been associated with various heritable anatomical and developmental abnormalities.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.