TCF3 Break Apart FISH Probe Kit - 10 tests

The TCF3 Break Apart FISH Probe Kit is designed to detect rearrangements in the human TCF3 gene located on chromosome band 19p13.3.* In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other TCF3 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the TCF3 gene – also known as E2A, E47, ITF1, VDIR, TCF-3 or bHLHb21 – have been observed in adult and pediatric B-cell leukemias and other tumor types.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

For Research Use Only.