TFE3 Break Apart FISH Probe Kit - 10 tests

The TFE3 FISH probe set is designed to detect rearrangements involving regions of the human TFE3 gene, located on chromosome band Xp11.23. The kit contains a pair of differentially labeled Locus Specific Probes (LSP), one covering the 5’ (start) portion of the TFE3 gene and some adjacent genomic sequences, the other covering the 3’ (end) part as well as sequences downstream of the gene. The two probes are flanking sequences across the TFE3 gene in which variable breakpoints have been observed. In addition to revealing breaks, which lead to translocation of parts of the gene, or its fusion to other genes, the probe set can also be used to identify other aberrations such as deletions or amplifications at the TFE3 locus.

For Research Use Only.