CytoTest NTRK1 Break Apart FISH Probe KitCT-PAC143-10-OG
The NTRK1 Break Apart FISH Probe Kit is designed to detect rearrangements in the human NTRK1 gene located on chromosome band 1q23.1. In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other NTRK1 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the NTRK1 gene – also known as MTC, TRK, TRK1, TRKA, Trk-A or p140-TrkA – have been observed in papillary thyroid carcinoma and other malignancies.
Intended Use: To detect rearrangements in the human NTRK1
gene located on chromosome band 1q23.1.
10 Tests (100μL)
LSP NTRK1 5' FISH Probe: CytoOrange
LSP NTRK1 3' FISH Probe: CytoGreen
LSP NTRK1 5’ FISH Probe covers sequences adjacent to the 5’ (start) portion of the NTRK1 gene. LSP NTRK1 3' FISH Probe covers some sequences downstream (3’ end) of the gene. The two probes are flanking sequences across the NTRK1 gene in which variable breakpoints have been observed.